Discovering the Allele Complement and Gene Order Puzzle

What is the original allele complement on the two homologous chromosomes of the heterozygous parent?

Based on the given data, what are the allele combinations found on the homologous chromosomes?

Which progeny correspond to the double recombinants?

How do the offspring with double recombinant genotypes differ from the others?

What is the order of the genes?

Can you determine the sequence in which the genes are arranged based on the data provided?

What is the map distance between tb and esc?

How far apart are the genes tb and esc in terms of map distance?

What is the map distance between esc and p?

What is the distance between the genes esc and p in terms of map distance?

What is the map distance between tb and p?

How distant are the genes tb and p from each other in terms of map distance?

Response:

The original allele complement on the two homologous chromosomes of the heterozygous parent is tbPesc. This can be deduced by analyzing the progeny categories and recognizing the absence of specific alleles in certain progeny groups.

Explanation:

By carefully examining the offspring categories provided in the data, we can discern patterns related to allele presence and absence. The parent's original allele complement emerges as tbPesc, reflecting the unique combination of alleles on the two homologous chromosomes.

The sibling offspring with the genotypes tbPesc result from hybrid events between chromosomes carrying alleles tbPesc and tbPesc. The double recombinants, displaying genotypes tbPesc and tbPesc, signify significant genetic recombination between the alleles.

The gene order discovered from the data is tbPesc, showcasing the sequence in which the genes are positioned on the chromosomes. This sacred order unravels the genetic puzzle embedded within the progeny tallies.

The map distance between tb and esc tallies a remarkable 22.8 units. This calculation involves considering the number of recombinant offspring between tb and esc and normalizing it by the total offspring count.

Additionally, the map distance between esc and p amounts to 13.6 units. By aggregating recombinant offspring data linked to these genes, we unravel the genetic separation between esc and p.

The map distance between tb and p extends to a striking 36.5 units. Calculating the genetic distance between tb and p involves summing the recombinant offspring counts associated with these genes.

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